Description

17Alpha-Neriifolin is a specialized cardiac glycoside compound of significant interest in pharmaceutical research and development. Its unique structure makes it a valuable reference standard and a key intermediate for synthesizing novel therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, well-characterized materials for critical applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in drug development and manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a crucial building block in the synthesis of novel cardiac glycoside-based therapeutics.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate mechanisms of action related to sodium-potassium ATPase inhibition and cardiac activity.
• Analytical Chemistry: Utilized as an analytical standard in HPLC, LC-MS, and NMR for the identification and quantification of related compounds in complex matrices.
• Preclinical Development: Provides a high-purity starting material for pharmacokinetic, pharmacodynamic, and toxicology studies.

Basic Information

Product Name	17Alpha-Neriifolin
CAS No.	7044-31-7
Molecular Formula	C30H46O8
Molecular Weight	534.69 g/mol
Synonyms	17α-Neriifolin; 17α-Hydroxy-14β-card-20(22)-enolide 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-; 17α-Hydroxy-14β-card-20(22)-enolide 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-, (3β,5β,17α)-; Neriifolin, 17α-; 17-epi-Neriifolin
EINECS	Contact for details

Quality Control

Every batch of 17Alpha-Neriifolin is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting its use in regulated environments. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and MS is supplied with each shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.