Description

6-Hydroxy-7-Methoxycoumarin is a functionalized coumarin derivative, a key intermediate in organic synthesis and pharmaceutical research. This compound matters for its role as a versatile building block in the development of bioactive molecules, including potential pharmaceuticals, agrochemicals, and fluorescent probes. Industries that need it include pharmaceutical R&D, fine chemical manufacturing, and academic research institutions focused on medicinal chemistry and natural product synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs) with potential therapeutic properties.
• Fluorescent Probe Development: Used in research to create sensitive fluorescent markers and sensors for biological and chemical detection due to its inherent fluorophore structure.
• Agrochemical Synthesis: Serves as a building block for developing new pesticides, herbicides, and plant growth regulators.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, dyes, and complex organic molecules.
• Biochemical Research: Utilized in studies of enzyme inhibition, receptor binding, and other biochemical pathways.
• Cosmetic Ingredient Research: Investigated for potential use in skincare formulations, often related to its UV-absorbing or antioxidant properties derived from the coumarin core.

Basic Information

Product Name	6-Hydroxy-7-Methoxycoumarin
CAS No.	776-86-3
Molecular Formula	C₁₀H₈O₄
Molecular Weight	192.17 g/mol
Synonyms	6-Hydroxy-7-methoxy-2H-chromen-2-one; 7-Methoxy-6-hydroxycoumarin; Esculetin 7-methyl ether; 6-Hydroxy-7-methoxy-1-benzopyran-2-one; Cichoriin aglycone; 6-Hydroxy-7-methoxychromen-2-one; Isofraxidin (Note: Isofraxidin typically refers to 6,8-dimethoxy-7-hydroxycoumarin; this is a common misassignment for the 6-hydroxy-7-methoxy isomer)
EINECS	212-299-8

Quality Control

Our 6-Hydroxy-7-Methoxycoumarin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	228°C - 232°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.