Description

5,6-Difluoro-Indoline-2,3-Dione is a high-purity, light-sensitive fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique difluoro-substituted isatin core structure makes it a valuable precursor for developing novel pharmaceuticals and agrochemicals with enhanced biological activity and metabolic stability. This intermediate is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used as a building block for creating new-generation herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for synthesizing specialized fluorinated organic materials and dyes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new fluorination chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5,6-Difluoro-Indoline-2,3-Dione
CAS No.	774-47-0
Molecular Formula	C8H3F2NO2
Molecular Weight	183.11 g/mol
Synonyms	5,6-Difluoro-1H-indole-2,3-dione; 5,6-Difluoro-2,3-dihydro-1H-indole-2,3-dione; 5,6-Difluoro-2,3-dioxoindoline; 5,6-Difluoroindoline-2,3-dione; 5,6-Difluoroisatin; 5,6-Difluoro-1H-indole-2,3-dione; 2,3-Dihydro-5,6-difluoro-1H-indole-2,3-dione
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-Indoline-2,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.