Description

(S)-3-Phenyl-1,3-Butanediol CAS NO 770-88-7 is a high-purity chiral diol building block of significant importance in asymmetric synthesis. Its value lies in its utility as a key intermediate for constructing complex molecules with defined stereochemistry, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and other therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric excess.
• Fine Chemical Production: Used in the manufacture of advanced fragrances, flavors, and other high-value specialty chemicals where optical purity is critical.
• Agrochemical Research: Employed as a precursor in the development of novel, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Acts as a scaffold for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	(S)-3-Phenyl-1,3-Butanediol
CAS No.	770-88-7
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(S)-3-Phenylbutane-1,3-diol; (S)-1,3-Dihydroxy-3-phenylbutane; (S)-3-Phenyl-1,3-butanediol; (S)-β-Hydroxy-β-methylbenzenepropanol; (S)-HMPP; (S)-3-Phenylbutanediol; (S)-3-PBD; L-3-Phenyl-1,3-butanediol
EINECS	212-241-5

Quality Control

Our (S)-3-Phenyl-1,3-Butanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, standard identity confirmation, and impurity profiling to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, specific rotation, and chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.