Description

1-(Chloromethyl)Adamantane is a versatile and highly functionalized adamantane derivative, serving as a critical building block in advanced organic synthesis. Its unique cage-like structure and reactive chloromethyl group make it invaluable for introducing the rigid, lipophilic adamantyl moiety into target molecules. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of adamantane-based antiviral drugs (e.g., derivatives of amantadine and rimantadine), neuroprotective agents, and other bioactive molecules.
• Agrochemical Synthesis: Used to create novel pesticides and fungicides with enhanced stability and bioavailability due to the adamantane scaffold.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing high-temperature resistant polymers, specialty resins, and advanced materials with unique thermal and mechanical properties.
• Ligand & Catalyst Development: Serves as a backbone for constructing bulky, electron-donating phosphine ligands used in homogeneous catalysis.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions to readily incorporate the adamantyl group, modifying the physical and chemical properties of target compounds.
• Research & Development: Essential tool compound in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies and probe development.

Basic Information

Product Name	1-(Chloromethyl)Adamantane
CAS No.	770-70-7
Molecular Formula	C11H17Cl
Molecular Weight	184.70 g/mol
Synonyms	1-Adamantylmethyl chloride; (Adamantan-1-yl)methyl chloride; 1-Chloromethyladamantane; 1-Adamantylmethyl chloride; Adamantane-1-methylene chloride; 1-(Chloromethyl)tricyclo[3.3.1.13,7]decane; NSC 221986
EINECS	212-235-6

Quality Control

Our 1-(Chloromethyl)Adamantane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.