Description

2,3,5,6-Tetrafluorothiophenol is a highly fluorinated aromatic thiol compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a thiol group on a perfluorinated benzene ring, makes it an essential precursor for introducing sulfur and fluorine functionalities into complex molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise molecular modifications to develop new active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in creating sulfur-containing bioactive molecules with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved lipophilicity and biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands in transition metal catalysis, useful in cross-coupling and other fine chemical reactions.
• Polymer and Material Science: Incorporated into monomers for creating specialty polymers with unique surface properties, chemical resistance, and potential use in electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and constructing complex heterocyclic systems.

Basic Information

Product Name	2,3,5,6-Tetrafluorothiophenol
CAS No.	769-40-4
Molecular Formula	C6H2F4S
Molecular Weight	182.14 g/mol
Synonyms	2,3,5,6-Tetrafluorobenzenethiol; Perfluorobenzene-1-thiol; 2,3,5,6-Tetrafluorophenyl mercaptan; Tetrafluorothiophenol; 769-40-4; Benzenethiol, 2,3,5,6-tetrafluoro-; SH-Tetrafluorobenzene
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluorothiophenol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Due to its sensitivity, the container should be kept tightly sealed when not in use to minimize oxidation and exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.