Description

1-Iodoadamantane is a halogenated derivative of the rigid, cage-like adamantane structure, serving as a versatile and valuable building block in advanced organic synthesis. Its unique steric and electronic properties make it an essential precursor for creating complex molecular architectures, particularly in pharmaceutical and materials science research. This high-purity intermediate is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to the development of advanced polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and antiviral therapies.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the adamantane core can enhance stability and biological activity.
• Materials Science Research: Serves as a precursor for creating functionalized adamantane units used in high-performance polymers, lubricants, and diamond-like carbon (DLC) coatings.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in organometallic chemistry due to its ability to impart steric bulk.
• Radiopharmaceuticals: The iodine atom provides a potential site for radioiodination, making it a candidate for developing diagnostic imaging agents.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	1-Iodoadamantane
CAS No.	768-93-4
Molecular Formula	C10H15I
Molecular Weight	262.13 g/mol
Synonyms	1-Iodoadamantane; Adamantane, 1-iodo-; 1-Adamantyl iodide; Iodoadamantane; 1-Iodoadamantane; 1-Iodotricyclo[3.3.1.13,7]decane; NSC 51128
EINECS	212-196-5

Quality Control

Our 1-Iodoadamantane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	115 - 120 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.