Description

2-Bromo-5-Methylthiophene is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactivity, serving as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional polymers. The product is supplied under stringent quality control to ensure reliability and consistency for critical B2B applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its thiophene core's bioactivity.
• Material Science: Serves as a monomer or building block for conductive polymers, organic semiconductors, and liquid crystal displays (LCDs).
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) to introduce the 2-bromo-5-methylthiophene moiety into more complex molecules.
• Chemical Research: A valuable reagent for academic and industrial R&D in heterocyclic and medicinal chemistry.
• Dye and Pigment Industry: Acts as an intermediate in the production of specialized dyes and organic pigments.

Basic Information

Product Name	2-Bromo-5-Methylthiophene
CAS No.	765-58-2
Molecular Formula	C5H5BrS
Molecular Weight	177.06 g/mol
Synonyms	5-Methyl-2-bromothiophene; 2-Bromo-5-methylthiophene; 5-Methylthiophene-2-bromide; 2-Brom-5-methylthiophen; Thiophene, 2-bromo-5-methyl-; NSC 404087; Bromo(5-methyl-2-thienyl)
EINECS	212-153-8

Quality Control

Our 2-Bromo-5-Methylthiophene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.560 - 1.570
Density (20°C)	1.55 - 1.65 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.