Description

1-Fluoro-2-Iodoethane is a versatile halogenated ethane derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both fluorine and iodine atoms, makes it an exceptionally valuable reagent for introducing fluoroalkyl and iodoalkyl groups into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in nucleophilic substitution reactions, cross-coupling chemistry, and the synthesis of complex fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluorinated active pharmaceutical ingredients (APIs) and diagnostic agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides where the fluorine moiety enhances biological activity and stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Fluorination Reagent: Acts as a source of fluoroethyl groups in nucleophilic fluorination reactions under various conditions.
• Cross-Coupling Chemistry: The iodine atom facilitates participation in palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings for carbon-carbon bond formation.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of biomolecules for metabolic pathway studies and imaging.

Basic Information

Product Name	1-Fluoro-2-Iodoethane
CAS No.	762-51-6
Molecular Formula	C2H4FI
Molecular Weight	189.96 g/mol
Synonyms	2-Fluoroethyl Iodide; Fluoroethyl Iodide; 1-Fluoro-2-iodoethane; 2-Iodoethyl Fluoride; Ethane, 1-fluoro-2-iodo-; Iodofluoroethane; β-Fluoroethyl Iodide; (2-Iodoethyl)fluoride
EINECS	212-099-3

Quality Control

Our 1-Fluoro-2-Iodoethane is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for production, ensuring reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place, away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 2°C and 8°C (refrigerated) to maximize stability. Keep the container tightly sealed when not in use to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Density (at 20°C)	~2.1 g/mL
Refractive Index (n20D)	~1.52

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.