Description

Acetic Acid-D CAS NO 758-12-3 is a deuterated isotopologue of acetic acid, where the hydrogen atoms are replaced with deuterium. This compound is essential for advanced research and analytical applications where isotopic labeling is required to study reaction mechanisms, metabolic pathways, or to serve as an internal standard. It is a critical reagent for NMR spectroscopy, pharmaceutical research, and the synthesis of labeled compounds in academic, biotechnology, and chemical industries.

Application

• NMR Spectroscopy Solvent & Standard: Used as a deuterated solvent for proton NMR to provide a lock signal and minimize interference from solvent protons.
• Pharmaceutical Research & Development: Employed as a tracer in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of molecules.
• Organic Synthesis & Catalysis: Serves as a labeled reagent or catalyst in mechanistic studies of acid-catalyzed reactions, including esterifications and condensations.
• Analytical Chemistry: Functions as a high-purity internal standard in mass spectrometry (MS) and liquid chromatography (LC) for accurate quantification.
• Material Science Research: Utilized in the study of polymer chemistry and surface science where isotopic effects are investigated.
• Biochemical & Metabolic Studies: Applied in tracing biochemical pathways and enzymatic reactions in vitro.

Basic Information

Product Name	Acetic Acid-D
CAS No.	758-12-3
Molecular Formula	C₂D₄O₂
Molecular Weight	64.08 g/mol
Synonyms	Deuteroacetic Acid; Acetic-d4 Acid; Perdeuteroacetic Acid; Deuterated Acetic Acid; [2H4]Acetic Acid; Glacial Acetic Acid-d4; Ethanoic-d4 Acid; D4-Acetic Acid
EINECS	Contact for details

Quality Control

Our Acetic Acid-D is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analysis to ensure high isotopic purity and chemical integrity, meeting the exacting requirements of research and analytical applications. Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, ensure containers are kept upright and away from heat, sparks, and incompatible materials such as strong bases and oxidizers.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Isotopic Purity (D-atom %)	≥ 99.5%
Chemical Purity (Assay by GC)	≥ 99.9%
Water Content (Karl Fischer)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.