Description

Trimethyldifluorophosphorane is a highly reactive organophosphorus compound primarily used as a versatile fluorinating and methylating agent in advanced chemical synthesis. Its value lies in its ability to introduce fluorine atoms and methyl groups under controlled conditions, which is critical for modifying molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the fluorination and methylation of complex organic molecules in drug discovery and development.
• Agrochemical Production: Used in the synthesis of advanced pesticides and herbicides where fluorine incorporation enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine ligands and organometallic catalysts.
• Material Science Research: Employed in the development of fluorine-containing polymers and advanced electronic materials.
• Organic Synthesis: A valuable tool for synthetic chemists for selective fluorination reactions in laboratory-scale and process chemistry.
• Chemical Vapor Deposition (CVD): Potential use as a precursor for depositing thin films containing phosphorus and fluorine.

Basic Information

Product Name	Trimethyldifluorophosphorane
CAS No.	753-59-3
Molecular Formula	C₃H₉F₂P
Molecular Weight	114.08 g/mol
Synonyms	Difluorotrimethylphosphorane; Trimethylphosphorane Difluoride; Phosphorane, difluorotrimethyl-; (Dimethylphosphino)dimethylfluorophosphorane; TMPF₂
EINECS	Contact for details

Quality Control

Our Trimethyldifluorophosphorane is produced and handled under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by NMR and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for all shipments to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.