Description

1-Ethyl-2-Methyl-5-[(Trifluoromethyl)Sulfonyl]-1H-Benzimidazole is a high-value, functionalized benzimidazole derivative characterized by its trifluoromethylsulfonyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the introduction of unique electronic and steric properties into target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the benzimidazole core and fluorinated group enhance biological activity and stability.
• Organic Electronics: Serves as a precursor for electron-deficient materials in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Research: Acts as a valuable substrate for studying structure-activity relationships (SAR) in medicinal and materials chemistry due to its trifluoromethylsulfonyl moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for proprietary synthesis projects.

Basic Information

Item	Detail
Product Name	1-Ethyl-2-Methyl-5-[(Trifluoromethyl)Sulfonyl]-1H-Benzimidazole
CAS No.	732-20-7
Molecular Formula	C11H11F3N2O2S
Molecular Weight	292.28 g/mol
Synonyms	5-[(Trifluoromethyl)sulfonyl]-1-ethyl-2-methyl-1H-benzimidazole; 1-Ethyl-2-methyl-5-(trifluoromethylsulfonyl)benzimidazole; 1H-Benzimidazole, 1-ethyl-2-methyl-5-[(trifluoromethyl)sulfonyl]-; 732-20-7; TFM-BIm; Ethyl Methyl Triflyl Benzimidazole
EINECS	Contact for details

Quality Control

Our 1-Ethyl-2-Methyl-5-[(Trifluoromethyl)Sulfonyl]-1H-Benzimidazole is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting specifications for research and production use. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.