Description

2,3-Dihydro-6-(Trifluoromethyl)Benzo[1,4]-Thiazin-3-One is a high-value heterocyclic building block characterized by its fused benzothiazine core and a strategically positioned trifluoromethyl group. This compound is prized for its role as a key synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs), where the CF₃ moiety is critical for modulating lipophilicity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzothiazinone scaffold.
• Material Science: Used in the research and development of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Synthesis: Acts as a versatile synthon for further functionalization, enabling the creation of complex heterocyclic libraries for high-throughput screening in drug discovery.
• Ligand & Catalyst Development: The structure can be modified to create novel ligands for transition metal catalysis or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2,3-Dihydro-6-(Trifluoromethyl)Benzo[1,4]-Thiazin-3-One
CAS No.	716-82-5
Molecular Formula	C₉H₆F₃NOS
Molecular Weight	233.21 g/mol
Synonyms	6-(Trifluoromethyl)-3,4-dihydro-2H-1,4-benzothiazin-3-one; 6-(Trifluoromethyl)-2H-1,4-benzothiazin-3(4H)-one; 2,3-Dihydro-6-(trifluoromethyl)-4H-1,4-benzothiazin-3-one; 6-Trifluoromethyl-3,4-dihydro-2H-benzo[1,4]thiazin-3-one; 3-Oxo-6-trifluoromethyl-3,4-dihydro-2H-1,4-benzothiazine; 716-82-5; Benzo[1,4]thiazin-3-one, 2,3-dihydro-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-6-(Trifluoromethyl)Benzo[1,4]-Thiazin-3-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.