Description

4-(3-Fluoro-4-Methoxyphenyl)-1,3-Thiazol-2-Amine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a fluorinated methoxyphenyl moiety with a 2-aminothiazole scaffold, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a crucial building block in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Material Science Precursor: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	4-(3-Fluoro-4-Methoxyphenyl)-1,3-Thiazol-2-Amine
CAS No.	716-75-6
Molecular Formula	C10H9FN2OS
Molecular Weight	224.25 g/mol
Synonyms	2-Amino-4-(3-fluoro-4-methoxyphenyl)thiazole; 4-(3-Fluoro-4-methoxyphenyl)-2-thiazolamine; 2-Thiazolamine, 4-(3-fluoro-4-methoxyphenyl)-; 4-(3-Fluoro-4-methoxyphenyl)thiazol-2-amine; 4-(3-Fluoro-4-methoxyphenyl)-2-aminothiazole; 716-75-6; AKOS BBS-00004316; FT-0658081; EN300-196077; A804099
EINECS	Contact for details

Quality Control

Our 4-(3-Fluoro-4-Methoxyphenyl)-1,3-Thiazol-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.