Description

3,3-Dichloromethyloxolane is a versatile chlorinated heterocyclic compound primarily valued as a key intermediate and building block in advanced organic synthesis. Its reactive dichloromethyl group makes it a crucial precursor for the development of pharmaceuticals, agrochemicals, and specialty polymers. This high-purity chemical is essential for research and production chemists in the fine chemical, pharmaceutical, and material science industries seeking to introduce functionalized oxolane moieties into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing tetrahydrofuran or functionalized ether structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the chloromethyloxolane unit contributes to biological activity.
• Polymer & Resin Modifier: Acts as a reactive monomer or cross-linking agent in the manufacture of specialty polymers, coatings, and adhesives to alter physical properties.
• Organic Synthesis Reagent: Employed in research laboratories for cyclization reactions, nucleophilic substitutions, and as a precursor to various aldehydes and acids via hydrolysis.
• Ligand & Catalyst Development: Utilized in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated for creating novel organic frameworks and functional materials with specific electronic or structural characteristics.

Basic Information

Product Name	3,3-Dichloromethyloxolane
CAS No.	78-71-7
Molecular Formula	C5H8Cl2O
Molecular Weight	155.02 g/mol
Synonyms	3,3-Bis(chloromethyl)oxolane; 3,3-Bis(chloromethyl)tetrahydrofuran; Tetrahydro-3,3-bis(chloromethyl)furan; 3,3-Dichloromethyltetrahydrofuran; Oxolane, 3,3-bis(chloromethyl)-; NSC 60529
EINECS	201-135-5

Quality Control

Our 3,3-Dichloromethyloxolane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.25 - 1.30 g/mL
Refractive Index (n20D)	1.480 - 1.490

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.