Description

Triphenylsilyl chloride is a versatile organosilicon reagent widely used as a key protecting group and intermediate in advanced organic synthesis. Its primary value lies in its ability to introduce the bulky, lipophilic triphenylsilyl group, which provides excellent steric protection for sensitive functional groups like alcohols and amines. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the production of complex molecules, fine chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical reagent in multi-step synthesis for protecting hydroxyl groups during the production of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides where selective protection of functional groups is required.
• Polymer & Material Science: Serves as a precursor or modifying agent in the synthesis of specialty silicones, silane coupling agents, and advanced polymeric materials.
• Organic Synthesis Reagent: Employed as a silylating agent in laboratory-scale and industrial-scale organic reactions to enhance selectivity and yield.
• Fine Chemical Production: Integral to the synthesis of fragrances, flavors, dyes, and other high-value specialty chemicals.
• Research & Development: A staple tool in academic and industrial R&D for method development and exploring new synthetic pathways.

Basic Information

Product Name	Triphenylsilyl Chloride
CAS No.	76-86-8
Molecular Formula	C18H15ClSi
Molecular Weight	294.85 g/mol
Synonyms	Chlorotriphenylsilane; Silane, chlorotriphenyl-; Triphenylchlorosilane; NSC 66199; TPSCl; Triphenylsilylchloride; Chlorotriphenylsilicon; Triphenylchlorosilicon
EINECS	200-995-2

Quality Control

Our Triphenylsilyl Chloride is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.