Description

1-Acetyl-5-(Morpholin-4-Ylsulfonyl)Indoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique indoline core functionalized with acetyl and morpholinosulfonyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Serves as a core structure in the synthesis of potential kinase inhibitors for oncology research.
• CNS Drug Discovery: Employed in the synthesis of compounds targeting neurological pathways and receptors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	1-Acetyl-5-(Morpholin-4-Ylsulfonyl)Indoline
CAS No.	698983-77-6
Molecular Formula	C15H20N2O4S
Molecular Weight	324.40 g/mol
Synonyms	1-Acetyl-5-(morpholinosulfonyl)indoline; 5-(Morpholine-4-sulfonyl)-2,3-dihydro-1H-indol-1-yl ethanone; N-[5-(Morpholin-4-ylsulfonyl)-2,3-dihydro-1H-indol-1-yl]acetamide; 1-Acetyl-5-morpholinosulfonylindoline; 698983-77-6; 1H-Indole-1-acetamide, N-[5-(4-morpholinylsulfonyl)-2,3-dihydro-; Ethanone, 1-[5-(4-morpholinylsulfonyl)-2,3-dihydro-1H-indol-1-yl]-
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-(Morpholin-4-Ylsulfonyl)Indoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.