Description

Bicyclo[2.2.2]Octanone, 6-Ethynyl-, (1R,4S,6R)-Rel- (9Ci) is a highly functionalized, stereochemically defined bicyclic ketone featuring a strategically positioned ethynyl group. This compound is a valuable and versatile chiral building block for advanced organic synthesis, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of novel, stereoselective pesticides and herbicides where the rigid bicyclic scaffold imparts specific biological activity.
• Ligand and Catalyst Development: The ethynyl and ketone functionalities make it a precursor for sophisticated ligands used in asymmetric catalysis.
• Material Science Research: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal or mechanical properties.
• Academic & R&D: Employed in methodological studies and total synthesis projects to explore new chemical transformations and build complex natural product analogs.

Basic Information

Product Name	Bicyclo[2.2.2]Octanone, 6-Ethynyl-, (1R,4S,6R)-Rel- (9Ci)
CAS No.	697747-89-0
Molecular Formula	C10H10O
Molecular Weight	146.19 g/mol
Synonyms	(1R,4S,6R)-6-Ethynylbicyclo[2.2.2]octan-2-one; rel-(1R,4S,6R)-6-Ethynylbicyclo[2.2.2]octan-2-one; 6-Ethynylbicyclo[2.2.2]octan-2-one (rel-(1R,4S,6R)-); Bicyclo[2.2.2]octan-2-one, 6-ethynyl-, (1R,4S,6R)-rel-; Chiral 6-Ethynylbicyclo[2.2.2]octanone
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.2]Octanone, 6-Ethynyl-, (1R,4S,6R)-Rel- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to ensure high chemical and enantiomeric purity, meeting the exacting standards required for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.