Description

(2-[(4-Oxopiperidin-1-Yl)Methyl]Phenyl)Boronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring a piperidinone moiety, makes it a valuable reagent for constructing complex molecular architectures, particularly in pharmaceutical research. This compound is essential for medicinal chemists and process development scientists working in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for forming carbon-carbon bonds, a fundamental reaction in constructing complex organic molecules.
• Medicinal Chemistry & Drug Discovery: Used extensively in high-throughput screening and the development of novel drug candidates due to its reactive boronic acid group and modifiable piperidinone ring.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and protein interactions.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and organic electronic materials.
• Agrochemical Synthesis: Employed in the research and development of new, more effective crop protection agents.

Basic Information

Product Name	(2-[(4-Oxopiperidin-1-Yl)Methyl]Phenyl)Boronic Acid
CAS No.	697739-42-7
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	1-[2-(Boronophenyl)methyl]-4-piperidinone; 2-[(4-Oxo-1-piperidinyl)methyl]benzeneboronic Acid; (2-((4-Oxopiperidin-1-yl)methyl)phenyl)boronic Acid; B-[2-[(4-Oxo-1-piperidinyl)methyl]phenyl]-Boronic Acid; 1-(2-Boronobenzyl)piperidin-4-one; 697739-42-7; AKOS005258065
EINECS	Contact for details

Quality Control

Our (2-[(4-Oxopiperidin-1-Yl)Methyl]Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.