Description

Pyrimidine-5-Boronic Acid Hemihydrate, 97% is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, catalyst development, and the synthesis of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential for creating complex molecular architectures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate pyrimidine motifs.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysts used in fine chemical production.
• Material Science Research: A building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	Pyrimidine-5-Boronic Acid Hemihydrate, 97%
CAS No.	696602-91-2
Molecular Formula	C4H5BN2O2 • 0.5H2O
Molecular Weight	123.91 g/mol (Anhydrous basis)
Synonyms	5-Pyrimidineboronic Acid Hemihydrate; Pyrimidin-5-ylboronic Acid Hemihydrate; 5-Boronopyrimidine Hemihydrate; (Pyrimidin-5-yl)boronic Acid Hemihydrate; 5-Pyrimidylboronic Acid Hemihydrate; 696602-91-2 (CAS); Pyrimidine-5-yl-B(OH)2 Hemihydrate
EINECS	Contact for details

Quality Control

Our Pyrimidine-5-Boronic Acid Hemihydrate, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation, NMR for structural verification, and Karl Fischer titration for moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.