Description

5-Fluoro-3-(Piperidin-3-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its unique heterocyclic scaffold, which combines indole and piperidine moieties, making it a versatile building block for medicinal chemistry. It is primarily utilized by research organizations and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• CNS Drug Development: Serves as a core scaffold for research into ligands for neurological receptors, potentially for treating disorders like depression, anxiety, or schizophrenia.
• Kinase Inhibitor Synthesis: Employed in the construction of potential kinase inhibitors for oncology research applications.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological processes and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Product Name	5-Fluoro-3-(Piperidin-3-Yl)-1H-Indole
CAS No.	695213-99-1
Molecular Formula	C13H15FN2
Molecular Weight	218.27 g/mol
Synonyms	5-Fluoro-3-(3-piperidinyl)-1H-indole; 3-(3-Piperidinyl)-5-fluoro-1H-indole; 5-Fluoro-3-piperidin-3-yl-1H-indole; 1H-Indole, 5-fluoro-3-(3-piperidinyl)-; 5-Fluoro-3-(piperidin-3-yl)indole; 5-Fluoro-3-(3-piperidyl)indole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(Piperidin-3-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.