Description

n-(3-Chloro-4-Fluorophenyl)-2-[(5-Methoxy-1H-Benzimidazol-2-Yl)Sulfanyl]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzimidazole-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Serves as a precursor for potential kinase inhibitors and other targeted cancer therapies.
• Antiviral Agent Synthesis: Employed in the research and development of new antiviral compounds.
• Biochemical Research: Used as a reference standard or probe in biochemical assays to study enzyme inhibition.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing custom synthesis for clients.

Basic Information

Product Name	n-(3-Chloro-4-Fluorophenyl)-2-[(5-Methoxy-1H-Benzimidazol-2-Yl)Sulfanyl]Acetamide
CAS No.	694486-91-4
Molecular Formula	C16H13ClFN3O2S
Molecular Weight	365.81 g/mol
Synonyms	2-[(5-Methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(3-chloro-4-fluorophenyl)acetamide; N-(3-Chloro-4-fluorophenyl)-2-[(5-methoxy-1H-benzimidazol-2-yl)thio]acetamide; 2-((5-Methoxy-1H-benzo[d]imidazol-2-yl)thio)-N-(3-chloro-4-fluorophenyl)acetamide; Acetamide, N-(3-chloro-4-fluorophenyl)-2-[(5-methoxy-1H-benzimidazol-2-yl)thio]-; CAS 694486-91-4
EINECS	Contact for details

Quality Control

Our n-(3-Chloro-4-Fluorophenyl)-2-[(5-Methoxy-1H-Benzimidazol-2-Yl)Sulfanyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.