Description

4-(Pyrimidin-4-Yl)Thiophen-2-Amine is a high-purity heterocyclic organic compound featuring a fused pyrimidine-thiophene structure, serving as a critical building block in advanced chemical synthesis. Its molecular architecture makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for its role in creating complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides that require specific heterocyclic motifs for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging agent in probe development for studying biological pathways and protein interactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthetic chemistry.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	4-(Pyrimidin-4-Yl)Thiophen-2-Amine
CAS No.	692891-75-1
Molecular Formula	C8H7N3S
Molecular Weight	177.23 g/mol
Synonyms	2-Amino-4-(pyrimidin-4-yl)thiophene; 4-(2-Aminothiophen-4-yl)pyrimidine; 4-Thiophen-2-amine, 4-(4-pyrimidinyl)-; 2-Amino-4-(4-pyrimidinyl)thiophene; 4-Pyrimidin-4-ylthiophen-2-amine; 692891-75-1; SCHEMBL11806279; BCP24733
EINECS	Contact for details

Quality Control

Our 4-(Pyrimidin-4-Yl)Thiophen-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO-guided conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.