Description

1-n-Boc-6-Methoxy-3-Methyl-1H-Indazole is a high-purity, advanced pharmaceutical intermediate featuring a protected indazole core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of small molecule therapeutics, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Serves as a protected scaffold for constructing indazole-based active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for target validation and biological pathway studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and novel heterocycle development.

Basic Information

Product Name	1-n-Boc-6-Methoxy-3-Methyl-1H-Indazole
CAS No.	691900-70-6
Molecular Formula	C14H18N2O3
Molecular Weight	262.31 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-6-methoxy-3-methyl-1H-indazole; tert-Butyl 6-methoxy-3-methyl-1H-indazole-1-carboxylate; 1-Boc-6-methoxy-3-methylindazole; 6-Methoxy-3-methyl-1H-indazole-1-carboxylic acid tert-butyl ester; Boc-6-methoxy-3-methylindazole; 1-(tert-Butoxycarbonyl)-6-methoxy-3-methyl-1H-indazole
EINECS	Contact for details

Quality Control

Our 1-n-Boc-6-Methoxy-3-Methyl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.