Description

1-(7-Iodo-Benzo[B]Thiophen-2-Yl)-Ethanone is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring both an iodo-substituted benzothiophene core and an acetyl group, makes it a versatile precursor for constructing complex molecules via cross-coupling and functional group transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides, herbicides, and fungicides, leveraging its reactive iodine atom for further structural elaboration.
• Material Science Research: Acts as a building block for the synthesis of organic electronic materials, such as novel semiconductors or light-emitting compounds for OLED applications.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands or organocatalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Can be used to develop molecular probes for studying biological systems and target identification.

Basic Information

Product Name	1-(7-Iodo-Benzo[B]Thiophen-2-Yl)-Ethanone
CAS No.	691888-17-2
Molecular Formula	C10H7IOS
Molecular Weight	302.13 g/mol
Synonyms	1-(7-Iodobenzo[b]thiophen-2-yl)ethanone; 2-Acetyl-7-iodobenzo[b]thiophene; 7-Iodo-2-acetylbenzothiophene; Ethanone, 1-(7-iodobenzo[b]thien-2-yl)-; 1-(7-Iodo-1-benzothiophen-2-yl)ethanone; 7-Iodo-2-acetylbenzo[b]thiophene; 2-Acetyl-7-iodobenzo[b]thiophene
EINECS	Contact for details

Quality Control

Our 1-(7-Iodo-Benzo[B]Thiophen-2-Yl)-Ethanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.