Description

(Z)-3-[1-(1,3-Thiazol-2-Yl)-1H-Pyrrol-2-Yl]-2-Propenoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining thiazole and pyrrole motifs. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting specific enzymatic pathways.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides due to its bioactive heterocyclic core.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique electronic or optical properties.
• Academic & R&D: Employed in organic chemistry research for studying heterocyclic coupling reactions and structure-activity relationships (SAR).
• Bioconjugation Chemistry: The propenoic acid moiety allows for potential use in linker technologies for antibody-drug conjugates (ADCs) or other bioconjugates.

Basic Information

Product Name	(Z)-3-[1-(1,3-Thiazol-2-Yl)-1H-Pyrrol-2-Yl]-2-Propenoic Acid
CAS No.	691887-94-2
Molecular Formula	C10H8N2O2S
Molecular Weight	220.25 g/mol
Synonyms	(Z)-3-(1-(Thiazol-2-yl)-1H-pyrrol-2-yl)acrylic acid; 2-Propenoic acid, 3-[1-(2-thiazolyl)-1H-pyrrol-2-yl]-, (Z)-; 3-[1-(1,3-Thiazol-2-yl)-1H-pyrrol-2-yl]acrylic acid (Z)-isomer; (Z)-3-(1-(1,3-Thiazol-2-yl)-1H-pyrrol-2-yl)acrylic acid; (2Z)-3-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]prop-2-enoic acid; CAS 691887-94-2
EINECS	Contact for details

Quality Control

Our (Z)-3-[1-(1,3-Thiazol-2-Yl)-1H-Pyrrol-2-Yl]-2-Propenoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.