Description

4-(Chloromethyl)-2-(3-Chlorophenyl)-1,3-Thiazole Hydrochloride is a high-purity, synthetically valuable organic intermediate. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or inflammatory conditions.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiazole core.
• Material Science: Used in the research and development of advanced organic materials, such as liquid crystals, organic semiconductors, or photoactive polymers.
• Chemical Synthesis: Employed in organic chemistry laboratories for constructing complex heterocyclic systems and for introducing the (chloromethyl)thiazole moiety into target molecules.
• Bioconjugation & Probe Development: The reactive chloromethyl group makes it suitable for creating chemical probes or for bioconjugation applications in biochemical research.

Basic Information

Product Name	4-(Chloromethyl)-2-(3-Chlorophenyl)-1,3-Thiazole Hydrochloride
CAS No.	690632-83-8
Molecular Formula	C10H8Cl2N2S • HCl
Molecular Weight	307.61 g/mol (Free base: 271.15 g/mol)
Synonyms	2-(3-Chlorophenyl)-4-(chloromethyl)thiazole hydrochloride; 4-(Chloromethyl)-2-(3-chlorophenyl)thiazole HCl; 1,3-Thiazole, 4-(chloromethyl)-2-(3-chlorophenyl)-, hydrochloride; 2-(3-Chlorophenyl)-4-(chloromethyl)-1,3-thiazole hydrochloride; 4-(Chloromethyl)-2-(m-chlorophenyl)thiazole hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-2-(3-Chlorophenyl)-1,3-Thiazole Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay purity and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable and traceable material for critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.