Description

3-Chloro-4-Methyl-2-Thiophenecarbonyl Chloride is a high-value, reactive organosulfur building block essential for advanced chemical synthesis. Its bifunctional nature, featuring both an acid chloride and a halogenated thiophene ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Active Ingredient Synthesis: Used to build thiophene-containing scaffolds for next-generation herbicides, fungicides, and insecticides.
• Material Science & Organic Electronics: Serves as a monomer for constructing conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and semiconductor materials.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom chemical synthesis services and scale-up production under cGMP conditions.
• Research & Development: Used in academic and industrial R&D for exploring new chemical reactions and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	3-Chloro-4-Methyl-2-Thiophenecarbonyl Chloride
CAS No.	690632-13-4
Molecular Formula	C7H4Cl2OS
Molecular Weight	207.08 g/mol
Synonyms	3-Chloro-4-methylthiophene-2-carbonyl chloride; 2-Thiophenecarbonyl chloride, 3-chloro-4-methyl-; 3-Chloro-4-methyl-2-thiophenecarboxylic acid chloride; 3-Chloro-4-methylthiophene-2-carboxylic acid chloride; 4-Methyl-3-chlorothiophene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Methyl-2-Thiophenecarbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our quality systems are designed to support development under research and cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.