Description

4-Bromo-2-Ethynyl-Thiophene is a high-value, multi-functional heterocyclic building block characterized by its reactive bromine and ethynyl substituents on a thiophene core. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures through cross-coupling and click chemistry reactions. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with tailored properties.
• Organic Electronic Materials: Serves as a crucial monomer or precursor for conjugated polymers and small molecules used in OLEDs, OFETs, and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis.
• Click Chemistry Substrate: The terminal alkyne group enables efficient Huisgen cycloaddition (azide-alkyne click) reactions for bioconjugation and polymer functionalization.
• Chemical Research & Development: A versatile building block for academic and industrial R&D exploring new heterocyclic chemistry and material properties.

Basic Information

Product Name	4-Bromo-2-Ethynyl-Thiophene
CAS No.	690266-87-6
Molecular Formula	C6H3BrS
Molecular Weight	187.06 g/mol
Synonyms	2-Ethynyl-4-bromothiophene; 4-Bromo-2-thienylacetylene; 4-Bromo-2-ethynylthiophene; 2-(Bromothiophen-4-yl)acetylene; Thiophene, 4-bromo-2-ethynyl-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Ethynyl-Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, guaranteeing traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.