Description

tert-Butyl 2-(1H-Indol-3-Yl)-2-Oxoethylcarbamate is a high-purity, protected amino acid derivative featuring an indole moiety, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and bioactive molecules. It is primarily sought after by research institutions and manufacturers engaged in peptide chemistry, medicinal chemistry, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting neurological and oncological pathways.
• Peptide Synthesis: Used as a protected glycine derivative for the solid-phase or solution-phase synthesis of complex peptides and peptidomimetics.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Bioconjugation: Acts as a versatile linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological processes.
• Agrochemical Research: Serves as an intermediate in the development of novel crop protection agents and plant growth regulators.

Basic Information

Product Name	tert-Butyl 2-(1H-Indol-3-Yl)-2-Oxoethylcarbamate
CAS No.	689232-04-0
Molecular Formula	C₁₅H₁₈N₂O₃
Molecular Weight	274.32 g/mol
Synonyms	Boc-3-(2-Oxo-2-aminoethyl)indole; N-(tert-Butoxycarbonyl)-2-(1H-indol-3-yl)-2-oxoethylamine; 2-[(tert-Butoxycarbonyl)amino]-2-(1H-indol-3-yl)ethan-1-one; tert-Butyl N-[2-(1H-indol-3-yl)-2-oxoethyl]carbamate; 2-(1H-Indol-3-yl)-2-oxoethyl carbamic acid tert-butyl ester; Boc-Gly(1H-Indol-3-yl)-OH ketone analog; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-(1H-indol-3-yl)-2-oxo-
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(1H-Indol-3-Yl)-2-Oxoethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.