Description

6-Bromo-4-Fluoroisoindoline is a high-purity, halogenated isoindoline derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the halogen atoms can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology: Utilized as a probe or labeling agent in biochemical research to study protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific halogenated isoindoline scaffolds.

Basic Information

Product Name	6-Bromo-4-Fluoroisoindoline
CAS No.	689214-92-4
Molecular Formula	C8H7BrFN
Molecular Weight	216.05 g/mol
Synonyms	4-Fluoro-6-bromo-2,3-dihydro-1H-isoindole; 6-Bromo-4-fluoro-2,3-dihydro-1H-isoindole; 1H-Isoindole, 6-bromo-4-fluoro-2,3-dihydro-; 689214-92-4; 4-Fluoro-6-bromoisoindoline; 6-Bromo-4-fluoroisoindoline; 6-Bromo-4-fluoro-isoindoline; 6-Bromo-4-fluoro-1H-isoindoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Fluoroisoindoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC-MS for residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.