Description

Thiophene-3-Ol, Tetrahydro-4-(2-Hydroxyethylidene)-, (3R)- (9Ci) is a chiral, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and chemical manufacturers focused on creating novel therapeutic agents, agrochemicals, and specialty materials where precise stereochemistry is critical for function.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders or anti-infective agents.
• Agrochemical Research: Serves as a building block for developing new pesticides or herbicides with enhanced efficacy and selectivity, leveraging its unique thiophene-based structure.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials due to the thiophene moiety.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Thiophene-3-Ol, Tetrahydro-4-(2-Hydroxyethylidene)-, (3R)- (9Ci)
CAS No.	688797-31-1
Molecular Formula	C8H12O2S
Molecular Weight	172.24 g/mol
Synonyms	(3R)-Tetrahydro-4-(2-hydroxyethylidene)thiophen-3-ol; 3-Thiophenanol, tetrahydro-4-(2-hydroxyethylidene)-, (3R)-; (R)-Tetrahydro-4-(2-hydroxyethylidene)thiophen-3-ol; 688797-31-1; (3R)-4-(2-Hydroxyethylidene)tetrahydrothiophen-3-ol; Tetrahydro-4-(2-hydroxyethylidene)-3-thiophenanol, (3R)-; Chiral thiophene alcohol derivative
EINECS	Contact for details

Quality Control

Every batch of Thiophene-3-Ol, Tetrahydro-4-(2-Hydroxyethylidene)-, (3R)- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and chiral intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.