Description

3-tert-Butoxycarbonylamino-5-(4-Ethoxyphenyl)Thiophene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in medicinal chemistry, enabling the development of novel therapeutic agents with specific target activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new drugs, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• API Synthesis: Serves as a crucial building block in the multi-step manufacturing process of complex Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and pharmacological research due to its functionalized thiophene core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3-tert-Butoxycarbonylamino-5-(4-Ethoxyphenyl)Thiophene-2-Carboxylic Acid
CAS No.	688763-50-0
Molecular Formula	C18H21NO5S
Molecular Weight	363.43 g/mol
Synonyms	3-((tert-Butoxycarbonyl)amino)-5-(4-ethoxyphenyl)thiophene-2-carboxylic acid; 5-(4-Ethoxyphenyl)-3-[(tert-butoxycarbonyl)amino]thiophene-2-carboxylic Acid; Boc-5-(4-Ethoxyphenyl)-2-thiophenecarboxylic Acid; N-Boc-5-(4-Ethoxyphenyl)thiophene-2-carboxylic Acid Amine; tert-Butyl [5-(4-ethoxyphenyl)-2-carboxythiophen-3-yl]carbamate; 688763-50-0; BOC-AEPA-Thiophene-2-COOH
EINECS	Contact for details

Quality Control

Our 3-tert-Butoxycarbonylamino-5-(4-Ethoxyphenyl)Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.