Description

Pyridoxine-D5 is a stable isotope-labeled analog of Vitamin B6, specifically deuterated at five positions, making it an essential internal standard for precise analytical quantification. This high-purity compound is critical for ensuring accuracy and reliability in mass spectrometry-based methods, eliminating variability and enhancing data integrity. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, clinical diagnostics, and nutritional science sectors for method development and validation.

Application

• Internal Standard for LC-MS/MS analysis of Vitamin B6 and its metabolites in biological matrices (plasma, serum, tissues).
• Quantitative analysis in pharmacokinetic and pharmacodynamic studies for drug development.
• Metabolomics and biomarker discovery research requiring high-precision isotope dilution techniques.
• Quality control and assurance testing in pharmaceutical manufacturing of vitamin supplements.
• Nutritional research and clinical studies investigating Vitamin B6 status and metabolism.
• Forensic and toxicology analysis for accurate compound identification and quantification.

Basic Information

Item	Detail
Product Name	Pyridoxine-D5
CAS No.	688302-31-0
Molecular Formula	C8H6D5NO3
Molecular Weight	174.20 g/mol
Synonyms	Vitamin B6-d5; Pyridoxine (ring-D5); 5-Deuteropyridoxine; 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol-d5; 3-Hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine-d5; Pyridoxol-d5; Pyridoxine hydrochloride-d5 (salt form); Deuterated Pyridoxine
EINECS	Contact for details

Quality Control

Our Pyridoxine-D5 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, isotopic enrichment, and impurity profile. We adhere to relevant industry standards for reference materials, and custom synthesis and purification to meet specific client requirements are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.