Description

3-Isoxazolecarboxamide, n-[3-(Aminocarbonyl)-4,5,6,7-Tetrahydrobenzo[B]Thien-2-Yl]-5-(4-Fluorophenyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in modern medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought after by R&D laboratories and pharmaceutical manufacturers engaged in synthesizing targeted small-molecule drugs, particularly those exploring central nervous system (CNS) and metabolic disorder pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• CNS Drug Development: Serves as a core scaffold in the development of potential therapeutics targeting neurological and psychiatric conditions.
• Kinase Inhibitor Synthesis: Employed in the construction of complex molecules designed to modulate specific kinase activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	3-Isoxazolecarboxamide, n-[3-(Aminocarbonyl)-4,5,6,7-Tetrahydrobenzo[B]Thien-2-Yl]-5-(4-Fluorophenyl)-
CAS No.	688050-42-2
Molecular Formula	C19H18FN3O2S
Molecular Weight	371.43 g/mol
Synonyms	N-[3-(Aminocarbonyl)-4,5,6,7-tetrahydro-1-benzothien-2-yl]-5-(4-fluorophenyl)-1,2-oxazole-3-carboxamide; 5-(4-Fluorophenyl)-N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]isoxazole-3-carboxamide; 5-(4-Fluorophenyl)-N-[3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1,2-oxazole-3-carboxamide; Tetrahydrobenzo[b]thiophene-3-carboxamide derivative; Isoxazole-thiophene carboxamide intermediate
EINECS	Contact for details

Quality Control

Our 3-Isoxazolecarboxamide intermediate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and impurity profiles against stringent in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.