Description

Bicyclo[2.2.1]Hept-2-En-2-Ol, 7,7-Dimethoxy-, (1R,4S)- (9Ci) is a high-purity, stereochemically defined bicyclic compound featuring a protected carbonyl group, making it a valuable chiral building block in advanced organic synthesis. Its rigid, functionalized norbornene-like structure is critical for constructing complex molecular architectures with precise spatial orientation. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where stereochemical control is paramount for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel, stereoselective pesticides and herbicides where the specific spatial configuration enhances biological activity and reduces environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique thermal or mechanical properties derived from its strained bicyclic framework.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic chemistry, particularly in studies involving ring-opening metathesis polymerization (ROMP) or Diels-Alder reactions.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex, naturally occurring terpenoid molecules with specific olfactory characteristics.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-2-En-2-Ol, 7,7-Dimethoxy-, (1R,4S)- (9Ci)
CAS No.	687976-50-7
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	(1R,4S)-7,7-Dimethoxybicyclo[2.2.1]hept-2-en-2-ol; (1R,4S)-7,7-Dimethoxy-2-norbornen-2-ol; (1R,4S)-2-Hydroxy-7,7-dimethoxy-2-norbornene; 7,7-Dimethoxy-2-norbornen-2-ol, (1R,4S)-; (1R,4S)-exo-7,7-Dimethoxy-2-norbornen-2-ol; Chiral Dimethoxy Norbornenol; (1R,4S)-DMB-NBE-ol
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-2-En-2-Ol, 7,7-Dimethoxy-, (1R,4S)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity, enantiomeric excess (e.e.), and consistent performance. Certificates of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral purity, and residual solvent levels are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.