Description

3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6,7-Dihydroxy-, Methyl Ester (9Ci) is a high-purity synthetic intermediate belonging to the tetrahydroisoquinoline class of compounds. This chemical is valued for its unique structural features, including the catechol (dihydroxy) moiety and ester functionality, which make it a versatile building block in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical development companies for the creation of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloids and potential drug candidates targeting neurological and cardiovascular systems.
• Chemical Research & Development: Serves as a critical scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Synthesis: Used in the preparation of chelating agents or ligands for catalytic and metal-binding applications due to its catechol group.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and advanced materials.
• Academic Research: Utilized in universities and research institutes for studying organic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6,7-Dihydroxy-, Methyl Ester (9Ci)
CAS No.	687619-47-2
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydro-6,7-dihydroxyisoquinoline-3-carboxylate; 1,2,3,4-Tetrahydro-6,7-dihydroxy-3-isoquinolinecarboxylic acid methyl ester; 6,7-Dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester; THIQ derivative; Catechol isoquinoline ester
EINECS	Contact for details

Quality Control

Every batch of 3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6,7-Dihydroxy-, Methyl Ester (9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.