Description

1H-Indole, 3-[[(4-Fluorophenyl)Methyl]Sulfonyl]-1-Methyl- CAS NO 686743-57-7 is a specialized sulfonyl indole derivative, a high-value synthetic intermediate designed for advanced research and development. This compound is engineered to provide a versatile and reactive scaffold for constructing complex molecules, offering significant value in fine chemical synthesis. It is primarily targeted for use by pharmaceutical and agrochemical R&D teams, as well as academic researchers focused on medicinal chemistry and novel material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its unique indole-sulfone structure.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery programs.
• Chemical Biology: Employed as a probe or tool compound in biochemical assays to study protein-ligand interactions and enzyme inhibition.
• Material Science Research: Investigated for its potential in creating novel organic electronic materials or advanced polymers due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical manufacturers for the production of client-specific target molecules.

Basic Information

Item	Detail
Product Name	1H-Indole, 3-[[(4-Fluorophenyl)Methyl]Sulfonyl]-1-Methyl-
CAS No.	686743-57-7
Molecular Formula	C16H14FNO2S
Molecular Weight	303.35 g/mol
Synonyms	1-Methyl-3-[(4-fluorobenzyl)sulfonyl]indole; 3-[(4-Fluorobenzyl)sulfonyl]-1-methyl-1H-indole; 1-Methyl-3-(4-fluorobenzylsulfonyl)indole; 1-Methylindole-3-(4'-fluorobenzyl) sulfone; N-Methyl-3-(p-fluorobenzylsulfonyl)indole; 686743-57-7; 3-((4-Fluorobenzyl)sulfonyl)-1-methyl-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole, 3-[[(4-Fluorophenyl)Methyl]Sulfonyl]-1-Methyl- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.