Description

5-Fluoro-3-(4-Methoxybenzylidene)-1,3-Dihydro-2H-Indol-2-One is a specialized heterocyclic organic compound featuring a fluorinated indolinone core, which is a key structural motif in medicinal chemistry. This compound matters as a high-value pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery programs and synthesis optimization.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged indolinone scaffold.
• Chemical Biology Probe: Acts as a tool compound for investigating biological pathways and protein interactions in academic and industrial research.
• Agrochemical Development: Employed in the research and synthesis of novel active ingredients for crop protection products.
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses to create complex, high-value specialty chemicals.
• Reference Standard: Provides a certified material for analytical method development, validation, and quality control in manufacturing.

Basic Information

Product Name	5-Fluoro-3-(4-Methoxybenzylidene)-1,3-Dihydro-2H-Indol-2-One
CAS No.	686726-22-7
Molecular Formula	C₁₆H₁₂FNO₂
Molecular Weight	269.27 g/mol
Synonyms	5-Fluoro-3-[(4-methoxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one; 3-(4-Methoxybenzylidene)-5-fluoroindolin-2-one; 5-Fluoro-3-(4-methoxybenzylidene)indolin-2-one; (5-Fluoro-2-oxoindolin-3-ylidene)(4-methoxyphenyl)methane; 686726-22-7; 5-Fluoro-3-(p-methoxybenzylidene)indolin-2-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity and strength confirmation. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports the needs of research and development, with specifications that can be aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.