Description

[4-[(4-Methylpiperidin-1-Yl)Sulfonyl]-1-Oxoisoquinolin-2(1H)-Yl]Acetic Acid CAS NO 685525-46-6 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel small-molecule drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Protease Inhibitor Development: The sulfonyl and oxoisoquinoline motifs suggest potential application in designing enzyme inhibitors.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or precursor for molecules targeting kinase signaling pathways.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	[4-[(4-Methylpiperidin-1-Yl)Sulfonyl]-1-Oxoisoquinolin-2(1H)-Yl]Acetic Acid
CAS No.	685525-46-6
Molecular Formula	C₁₇H₂₀N₂O₅S
Molecular Weight	364.42 g/mol
Synonyms	2-(4-((4-Methylpiperidin-1-yl)sulfonyl)-1-oxo-1,2-dihydroisoquinolin-2-yl)acetic acid; 2-[4-(4-Methylpiperidine-1-sulfonyl)-1-oxo-2H-isoquinolin-2-yl]acetic acid; 685525-46-6; 4-(4-Methylpiperidine-1-sulfonyl)-2-(carboxymethyl)isoquinolin-1-one; 1-Oxo-4-[(4-methyl-1-piperidinyl)sulfonyl]-2(1H)-isoquinolineacetic Acid
EINECS	Contact for details

Quality Control

Our production of [4-[(4-Methylpiperidin-1-Yl)Sulfonyl]-1-Oxoisoquinolin-2(1H)-Yl]Acetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.