Description

n-(1H-Indazol-4-Yl)-2-Thiophenesulfonamide CAS NO 685108-44-5 is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining indazole and thiophene sulfonamide moieties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• Biochemical Assay Development: Employed as a reference standard or probe molecule in high-throughput screening (HTS) and in vitro testing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	n-(1H-Indazol-4-Yl)-2-Thiophenesulfonamide
CAS No.	685108-44-5
Molecular Formula	C11H9N3O2S2
Molecular Weight	279.34 g/mol
Synonyms	4-(2-Thiophenesulfonamido)-1H-indazole; 2-Thiophenesulfonamide, N-(1H-indazol-4-yl)-; N-(1H-Indazol-4-yl)thiophene-2-sulfonamide; N-Indazol-4-yl-2-thiophenesulfonamide; 685108-44-5; Thiophene-2-sulfonic acid (1H-indazol-4-yl)amide
EINECS	Contact for details

Quality Control

Our n-(1H-Indazol-4-Yl)-2-Thiophenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.