Description

3-{5-(4-Bromophenyl)-1-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrol-2-Yl}Propanoic Acid CAS NO 683808-78-8 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating bromophenyl and trifluoromethylphenyl moieties. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Synthesis: Serves as a critical precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Potential use in developing probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	3-{5-(4-Bromophenyl)-1-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrol-2-Yl}Propanoic Acid
CAS No.	683808-78-8
Molecular Formula	C20H15BrF3NO2
Molecular Weight	438.24 g/mol
Synonyms	3-[5-(4-Bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl]propanoic acid; 3-(5-(4-Bromophenyl)-1-(2-(trifluoromethyl)phenyl)-1H-pyrrol-2-yl)propanoic Acid; 683808-78-8; Propanoic acid, 3-[5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl]-; 5-(4-Bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrole-2-propanoic Acid; 1H-Pyrrole-2-propanoic acid, 5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support development and cGMP-grade requirements, with specifications tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.