Description

2-[1-(3-Aminopropyl)-1H-Indol-3-Yl]-3-(1H-Indol-3-Yl)Maleimide, Hcl is a specialized bis-indole maleimide derivative, a compound class of significant interest in advanced organic synthesis and pharmaceutical research. Its molecular architecture makes it a valuable building block for developing novel bioactive molecules and functional materials. This product is primarily utilized by research chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential kinase inhibitors and other biologically active compounds targeting specific cellular pathways.
• Bioconjugation Reagent: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents due to its reactive maleimide and amine functional groups.
• Chemical Biology Probe: Acts as a core scaffold for creating fluorescent probes or activity-based protein profiling (ABPP) reagents to study enzyme function.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and dendrimers with unique optical or electronic properties.
• Agrochemical Research: Used as an intermediate in the development of new crop protection agents with novel modes of action.
• Material Science: Investigated for creating advanced organic electronic materials or as a cross-linking agent in specialty coatings.

Basic Information

Item	Details
Product Name	2-[1-(3-Aminopropyl)-1H-Indol-3-Yl]-3-(1H-Indol-3-Yl)Maleimide, Hcl
CAS No.	683775-59-9
Molecular Formula	C26H25ClN4O2
Molecular Weight	460.96 g/mol
Synonyms	2-[1-(3-Aminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide hydrochloride; Bisindolylmaleimide IX, Hydrochloride; BIM IX, HCl; 3-(1H-Indol-3-yl)-2-[1-(3-aminopropyl)-1H-indol-3-yl]maleimide hydrochloride; 2-[1-(3-Aminopropyl)indol-3-yl]-3-indol-3-ylmaleimide hydrochloride; Go 6983 analog; Protein Kinase C Inhibitor analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2-[1-(3-Aminopropyl)-1H-Indol-3-Yl]-3-(1H-Indol-3-Yl)Maleimide, Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for critical research and development applications. A Certificate of Analysis (COA) detailing specifications such as HPLC purity, NMR confirmation, and residual solvent content is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.