Description

4-Fluoro-3-Hydroxy (1H)Indazole is a high-purity fluorinated indazole derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique fluorinated indazole scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products, leveraging the bioactivity of the indazole core.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds to study biological pathways and protein function.
• Material Science Precursor: Potential building block for advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for use in custom synthesis projects and library production.

Basic Information

Product Name	4-Fluoro-3-Hydroxy (1H)Indazole
CAS No.	683748-50-7
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	4-Fluoro-1H-indazol-3-ol; 3-Hydroxy-4-fluoro-1H-indazole; 4-Fluoro-3-indazolol; 4-Fluoroindazol-3-ol; 683748-50-7; 4-Fluoro-3-hydroxyindazole; 3-Hydroxy-4-fluoroindazole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Hydroxy (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.