Description

Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl- is a high-purity, functionalized bicyclic amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and intermediate for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring rigid, stereodefined frameworks.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and fungicides with enhanced stereospecificity and biological activity.
• Ligand and Catalyst Development: Core structure for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioactive Molecule Design: Used to introduce conformational constraints into peptide analogs and other bioactive compounds to improve stability and potency.
• Material Science Research: Intermediate for synthesizing specialized monomers and polymers with unique thermal or mechanical properties.
• Academic and Industrial R&D: A valuable tool compound for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl-
CAS No.	683737-21-5
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	2-Amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid; 2-Amino-2,6,6-trimethyl-3-norcarenecarboxylic acid; Trimethylnorcarene amino acid; 3-Carboxy-2,6,6-trimethyl-2-aminonorcarene; 2-Amino-2,6,6-trimethyl-3-carboxynorcarene; (1S,2R,3S,5R)-2-Amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid (stereoisomer); Norcarene amino acid derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.