Description

3,4-Thiophenediol, Tetrahydro-2-Mercapto-, (2R,3S,4S)-Rel- (9Ci) is a high-purity, stereochemically defined sulfur-containing heterocyclic compound. This molecule is valued as a sophisticated chiral building block and ligand precursor in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Asymmetric Catalyst Ligand: Serves as a precursor for the synthesis of novel chiral ligands used in transition metal-catalyzed asymmetric reactions, such as hydrogenation and cross-coupling.
• Agrochemical Research: Used in the discovery and synthesis of new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Material Science Precursor: Employed in the development of advanced organic electronic materials and functional polymers where the thiophene and thiol moieties impart specific electronic properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions involving sulfur chemistry.

Basic Information

Item	Details
Product Name	3,4-Thiophenediol, Tetrahydro-2-Mercapto-, (2R,3S,4S)-Rel- (9Ci)
CAS No.	683278-62-8
Molecular Formula	C4H8OS2
Molecular Weight	136.23 g/mol
Synonyms	(2R,3S,4S)-Tetrahydro-2-mercapto-3,4-thiophenediol; rel-(2R,3S,4S)-Tetrahydro-2-mercapto-3,4-thiophenediol; Tetrahydro-2-mercapto-3,4-thiophenediol (2R,3S,4S)-rel-; 3,4-Thiophenediol, tetrahydro-2-mercapto-, (2R,3S,4S)-rel-; 683278-62-8; Chiral tetrahydrothiophenediol thiol; Mercapto-substituted tetrahydrothiophenediol
EINECS	Contact for details

Quality Control

Every batch of 3,4-Thiophenediol, Tetrahydro-2-Mercapto-, (2R,3S,4S)-Rel- (9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements of research and development. A detailed Certificate of Analysis (COA) including results for assay, enantiomeric excess, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.