Description

(E)-2-(4-(3,4-Dimethoxyphenyl)Thiazol-2-Yl)-3-(2-(Trifluoromethyl)Phenyl)Acrylonitrile is a high-value, structurally complex organic compound featuring a thiazole core, dimethoxyphenyl and trifluoromethylphenyl substituents, and an acrylonitrile moiety. This compound is primarily significant as a key advanced pharmaceutical intermediate or research chemical in the development of novel active ingredients. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and material science sectors seeking to incorporate its unique molecular architecture into new products.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides or herbicides, leveraging the biological activity of the thiazole and trifluoromethyl groups.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a precursor for electron-transport or emissive layer materials in display and lighting technologies.
• Chemical Biology Probe: Utilized in academic and industrial research to study biological pathways and protein interactions.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	(E)-2-(4-(3,4-Dimethoxyphenyl)Thiazol-2-Yl)-3-(2-(Trifluoromethyl)Phenyl)Acrylonitrile
CAS No.	683250-97-7
Molecular Formula	C21H15F3N2O2S
Molecular Weight	416.42 g/mol
Synonyms	(E)-2-[4-(3,4-Dimethoxyphenyl)-1,3-thiazol-2-yl]-3-[2-(trifluoromethyl)phenyl]prop-2-enenitrile; 2-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile; (E)-2-(4-(3,4-Dimethoxyphenyl)-2-thiazolyl)-3-(2-(trifluoromethyl)phenyl)-2-propenenitrile; 683250-97-7; (2E)-2-[4-(3,4-Dimethoxyphenyl)-1,3-thiazol-2-yl]-3-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
EINECS	Contact for details

Quality Control

Our production of (E)-2-(4-(3,4-Dimethoxyphenyl)Thiazol-2-Yl)-3-(2-(Trifluoromethyl)Phenyl)Acrylonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide detailed Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and may be moisture-sensitive; handling under an inert atmosphere is recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.