Description

2H-Benzimidazol-2-One, 4-Bromo-1,3-Dihydro-6-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its bromo and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the introduction of key structural motifs that influence bioactivity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Precursor for advanced polymers, liquid crystals, or organic electronic materials requiring specific halogenated and fluorinated benzimidazole cores.
• Chemical Biology: Useful in the design and synthesis of molecular probes and biochemical tools for studying enzyme mechanisms or cellular pathways.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for bespoke chemical synthesis services catering to client-specific molecular targets.

Basic Information

Product Name	2H-Benzimidazol-2-One, 4-Bromo-1,3-Dihydro-6-(Trifluoromethyl)-
CAS No.	683240-52-0
Molecular Formula	C8H4BrF3N2O
Molecular Weight	281.03 g/mol
Synonyms	4-Bromo-6-(trifluoromethyl)-1H-benzimidazol-2(3H)-one; 4-Bromo-6-(trifluoromethyl)-2-benzimidazolinone; 4-Bromo-6-trifluoromethyl-2-benzimidazolinone; 4-Bromo-6-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one; 683240-52-0; 4-Bromo-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one
EINECS	Contact for details

Quality Control

Our 2H-Benzimidazol-2-One, 4-Bromo-1,3-Dihydro-6-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.