Description

(3S)-3-Amino-3-(2-Thienyl)Propan-1-Ol CAS NO 683220-39-5 is a chiral amino alcohol building block featuring a thiophene heterocycle, which is critical for introducing specific stereochemistry and electronic properties into target molecules. This compound is highly valued in advanced organic synthesis for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Development: Used in the creation of advanced pesticides and herbicides where the thienyl moiety contributes to biological activity.
• Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis, enhancing reaction selectivity.
• Peptidomimetics Research: Incorporated into peptide analogs to modulate stability, bioavailability, and receptor binding affinity.
• Material Science: Potential building block for functionalized polymers and advanced organic materials with specific electronic characteristics.

Basic Information

Product Name	(3S)-3-Amino-3-(2-Thienyl)Propan-1-Ol
CAS No.	683220-39-5
Molecular Formula	C7H11NOS
Molecular Weight	157.23 g/mol
Synonyms	(S)-3-Amino-3-(2-thienyl)-1-propanol; (3S)-3-Amino-3-(thiophen-2-yl)propan-1-ol; 3-Amino-3-(2-thienyl)-1-propanol, (3S)-; 1-Propanol, 3-amino-3-(2-thienyl)-, (3S)-; (S)-3-Amino-3-(thiophen-2-yl)propan-1-ol; (S)-3-Amino-3-(2-thienyl)propanol; (S)-3-(2-Thienyl)-3-aminopropanol
EINECS	Contact for details

Quality Control

Our (3S)-3-Amino-3-(2-Thienyl)Propan-1-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and IR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.