Description

Indolizine, 1,2,3,5,6,8A-Hexahydro-5,6-Dimethyl-, (5R,6R,8As)- (9Ci) is a high-purity, stereochemically defined indolizine derivative, a versatile heterocyclic scaffold of significant interest in advanced organic synthesis. This compound is valued for its role as a key chiral building block and intermediate in the development of complex molecules with specific three-dimensional architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the indolizine core contributes to biological activity.
• Asymmetric Catalysis Ligand Synthesis: Acts as a starting material for constructing sophisticated chiral ligands used in enantioselective catalytic reactions.
• Material Science Research: Investigated as a monomer or functional unit for creating novel organic electronic materials or specialty polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and stereoselective chemistry.
• Fine Chemical Synthesis: Utilized in the multi-step production of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Indolizine, 1,2,3,5,6,8A-Hexahydro-5,6-Dimethyl-, (5R,6R,8As)- (9Ci)
CAS No.	682738-79-0
Molecular Formula	C10H16N
Molecular Weight	150.24 g/mol
Synonyms	(5R,6R,8aS)-5,6-Dimethyl-1,2,3,5,6,8a-hexahydroindolizine; (5R,6R,8aS)-5,6-Dimethyloctahydroindolizine; Hexahydro-5,6-dimethylindolizine (stereoisomer); Indolizine, hexahydro-5,6-dimethyl-, (5R,6R,8aS)-; (5R,6R,8aS)-5,6-Dimethyloctahydroindolizine; 682738-79-0; SCHEMBL21806227; DTXSID90672966
EINECS	Contact for details

Quality Control

Our Indolizine, 1,2,3,5,6,8A-Hexahydro-5,6-Dimethyl-, (5R,6R,8As)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (5R,6R,8aS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.